Sunday, December 21, 2014

Why Vaccine Formulation Development Is Important

By Stacey Burt


Medicine is a constantly advancing field of activity, and new medications and surgical procedures are sometimes highly unpredictable, or where they succeed, immensely impressive. Most of the time, patients treated using modern medicine are happy with the outcome. Be that as it may, there are still those conditions which cannot be effectively treated, and many of these are caused by infectious elements known as viruses. The modern response to viral infection and transmission is to develop a suitable medication, through vaccine formulation development.

Unlike other pathogens, a virus cannot be destroyed by an antibiotic, since, technically it is not alive (i. E. Biotic in nature). Also, it is a germ, so it cannot be eliminated through mechanical techniques such as surgery or ultrasound. The only effective known intervention is a vaccine.

A vaccine partially imitates the virus in the patient's body, so that the person's immune system starts to manufacture viral antibodies. The body does this in response to the detected threat of the pseudo-virus (the vaccine).

Viral antibodies are the body's natural defence against viruses. They are particles manufactured by the immune system which destroy viral particles. Only the human body has the ability to manufacture antibodies, and once they are present, the person can never be infected by that same virus again. Successful vaccination therefore enables the body to develop permanent resistance to a virus.

The process of the immunization of infants and young kids is based on this principle. They are typically immunized against common yet serious diseases like measles and polio. Immunization has become a standard practice, yet it is necessary. Smallpox and polio, two supposedly archaic names, used to be substantial threats to public health and maimed, disfigured or killed many people.

Some of the most serious diseases are viral in nature, such as the notorious Ebola, AIDS, viral meningitis (which sets in within 48 hours and has terrible symptoms), and, as stated above, polio. These are all potentially lethal infections. The development of vaccines to counter them is thus of extreme importance.

Once a vaccine has been formulated, however, the same virus may yet become a problem in the future. This occurs through the natural process of genetic mutation, during the reproduction of the virus. Viruses do this constantly, and so they may turn into a new form or strain, one which is not affected by the patient's antibodies. This sounds terrifying, but it is common. A prime example if the flu virus, which takes on a new strain every year, and so no vaccine has been developed for it. The common cold does the same. No pharmacological intervention lasts more than one season against these viruses, and immunization is therefore not a long-term solution to them.

As effective as a vaccine may be, the public should also be aware that sensible personal health habits are important too. Observing simple principles of personal safety and health are important in limiting or preventing infections and epidemics, especially where the disease is incurable, such as AIDS. In such cases, there is no vaccine, and so relying on one is neither an option nor is it necessary.




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